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Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression

The COP9 signalosome (CSN), an eight-subunit protein complex, is conserved in all higher eukaryotes. CSN intersects the ubiquitin–proteasome pathway, modulating signaling pathways controlling various aspects of development. We are using Drosophila as a model system to elucidate the function of this...

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Detalles Bibliográficos
Autores principales: Oron, Efrat, Tuller, Tamir, Li, Ling, Rozovsky, Nina, Yekutieli, Daniel, Rencus-Lazar, Sigal, Segal, Daniel, Chor, Benny, Edgar, Bruce A, Chamovitz, Daniel A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673709/
https://www.ncbi.nlm.nih.gov/pubmed/17486136
http://dx.doi.org/10.1038/msb4100150