Mammalian MCM Loading in Late-G(1) Coincides with Rb Hyperphosphorylation and the Transition to Post-Transcriptional Control of Progression into S-Phase

BACKGROUND: Control of the onset of DNA synthesis in mammalian cells requires the coordinated assembly and activation of the pre-Replication Complex. In order to understand the regulatory events controlling preRC dynamics, we have investigated how the timing of preRC assembly relates temporally to o...

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Detalles Bibliográficos
Autores principales: Mukherjee, Piyali, Cao, Thinh V., Winter, Sherry L., Alexandrow, Mark G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674209/
https://www.ncbi.nlm.nih.gov/pubmed/19421323
http://dx.doi.org/10.1371/journal.pone.0005462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674209/
https://www.ncbi.nlm.nih.gov/pubmed/19421323
http://dx.doi.org/10.1371/journal.pone.0005462

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