Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies

There is strong evidence that rare variants are involved in complex disease etiology. The first step in implicating rare variants in disease etiology is their identification through sequencing in both randomly ascertained samples (e.g., the 1,000 Genomes Project) and samples ascertained according to...

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Detalles Bibliográficos
Autores principales: Li, Bingshan, Leal, Suzanne M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674213/
https://www.ncbi.nlm.nih.gov/pubmed/19436704
http://dx.doi.org/10.1371/journal.pgen.1000481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674213/
https://www.ncbi.nlm.nih.gov/pubmed/19436704
http://dx.doi.org/10.1371/journal.pgen.1000481

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