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Expanding the Repertoire of Modified Vaccinia Ankara-Based Vaccine Vectors via Genetic Complementation Strategies

BACKGROUND: Modified Vaccinia virus Ankara (MVA) is a safe, highly attenuated orthopoxvirus that is being developed as a recombinant vaccine vector for immunization against a number of infectious diseases and cancers. However, the expression by MVA vectors of large numbers of poxvirus antigens, whic...

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Detalles Bibliográficos
Autores principales: Garber, David A., O'Mara, Leigh A., Zhao, Jun, Gangadhara, Sailaja, An, InChul, Feinberg, Mark B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674217/
https://www.ncbi.nlm.nih.gov/pubmed/19421328
http://dx.doi.org/10.1371/journal.pone.0005445