Molecular ageing in progeroid syndromes: Hutchinson-Gilford progeria syndrome as a model

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder that belongs to a group of conditions called laminopathies which affect nuclear lamins. Mutations in two genes, LMNA and ZMPSTE24, have been found in patients with HGPS. The p.G608G LMNA mutation is the most commonly repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Coutinho, Henrique Douglas M, Falcão-Silva, Vivyanne S, Gonçalves, Gregório Fernandes, da Nóbrega, Raphael Batista
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674425/
https://www.ncbi.nlm.nih.gov/pubmed/19379495
http://dx.doi.org/10.1186/1742-4933-6-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674425/
https://www.ncbi.nlm.nih.gov/pubmed/19379495
http://dx.doi.org/10.1186/1742-4933-6-4

Ejemplares similares