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Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives

BACKGROUND: Mouse embryonic stem (ES) cells remain pluripotent in vitro when grown in the presence of the cytokine Leukaemia Inhibitory Factor (LIF). Identification of LIF targets and of genes regulating the transition between pluripotent and early differentiated cells is a critical step for underst...

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Detalles Bibliográficos
Autores principales: Trouillas, Marina, Saucourt, Claire, Guillotin, Bertrand, Gauthereau, Xavier, Ding, Li, Buchholz, Frank, Doss, Michael Xavier, Sachinidis, Agapios, Hescheler, Jurgen, Hummel, Oliver, Huebner, Norbert, Kolde, Raivo, Vilo, Jaak, Schulz, Herbert, Bœuf, Hélène
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674464/
https://www.ncbi.nlm.nih.gov/pubmed/19203379
http://dx.doi.org/10.1186/1471-2164-10-73