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RNA Polymerase V transcription guides ARGONAUTE4 to chromatin

Retrotransposons and repetitive DNA elements in eukaryotes are silenced by small RNA-directed heterochromatin formation. In Arabidopsis, this process involves 24 nt siRNAs that bind to ARGONAUTE4 (AGO4) and facilitate the targeting of complementary loci1,2 via unknown mechanisms. Nuclear RNA Polymer...

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Detalles Bibliográficos
Autores principales: Wierzbicki, Andrzej T., Ream, Thomas, Haag, Jeremy R., Pikaard, Craig S.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674513/
https://www.ncbi.nlm.nih.gov/pubmed/19377477
http://dx.doi.org/10.1038/ng.365