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Multipotent Genetic Suppression of Retrotransposon-Induced Mutations by Nxf1 through Fine-Tuning of Alternative Splicing

Cellular gene expression machinery has coevolved with molecular parasites, such as viruses and transposons, which rely on host cells for their expression and reproduction. We previously reported that a wild-derived allele of mouse Nxf1 (Tap), a key component of the host mRNA nuclear export machinery...

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Detalles Bibliográficos
Autores principales: Concepcion, Dorothy, Flores-García, Lisbeth, Hamilton, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674570/
https://www.ncbi.nlm.nih.gov/pubmed/19436707
http://dx.doi.org/10.1371/journal.pgen.1000484