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Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses

BACKGROUND: Current literature suggests that dipeptidyl peptidase IV (DPP-IV; CD26) plays an essential role in T-dependent immune responses, a role that could have important clinical consequences. To rigorously define the role of DPP-IV in the immune system, we evaluated genetic and pharmacological...

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Detalles Bibliográficos
Autores principales: Vora, Kalpit A, Porter, Gene, Peng, Roche, Cui, Yan, Pryor, Kellyann, Eiermann, George, Zaller, Dennis M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674587/
https://www.ncbi.nlm.nih.gov/pubmed/19358731
http://dx.doi.org/10.1186/1471-2172-10-19