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Simultaneous fine mapping of closely linked epistatic quantitative trait loci using combined linkage disequilibrium and linkage with a general pedigree

Causal mutations and their intra- and inter-locus interactions play a critical role in complex trait variation. It is often not easy to detect epistatic quantitative trait loci (QTL) due to complicated population structure requirements for detecting epistatic effects in linkage analysis studies and...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hong, Werf, Julius HJ van der
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674901/
https://www.ncbi.nlm.nih.gov/pubmed/18400149
http://dx.doi.org/10.1186/1297-9686-40-3-265