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B7-H1 Blockade Increases Survival of Dysfunctional CD8(+) T Cells and Confers Protection against Leishmania donovani Infections

Experimental visceral leishmaniasis (VL) represents an exquisite model to study CD8(+) T cell responses in a context of chronic inflammation and antigen persistence, since it is characterized by chronic infection in the spleen and CD8(+) T cells are required for the development of protective immunit...

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Detalles Bibliográficos
Autores principales: Joshi, Trupti, Rodriguez, Susana, Perovic, Vladimir, Cockburn, Ian A., Stäger, Simona
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674929/
https://www.ncbi.nlm.nih.gov/pubmed/19436710
http://dx.doi.org/10.1371/journal.ppat.1000431