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B7-H1 Blockade Increases Survival of Dysfunctional CD8(+) T Cells and Confers Protection against Leishmania donovani Infections
Experimental visceral leishmaniasis (VL) represents an exquisite model to study CD8(+) T cell responses in a context of chronic inflammation and antigen persistence, since it is characterized by chronic infection in the spleen and CD8(+) T cells are required for the development of protective immunit...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674929/ https://www.ncbi.nlm.nih.gov/pubmed/19436710 http://dx.doi.org/10.1371/journal.ppat.1000431 |