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T cell sensitivity to TGF-β is required for the effector function but not the generation of splenic CD8(+) regulatory T cells induced via the injection of antigen into the anterior chamber
The introduction of antigen into the anterior chamber (AC) of the eye induces the production of antigen-specific splenic CD8(+) regulatory T cells (AC-SPL cells) that suppress a delayed-type hypersensitivity (DTH) reaction in immunized mice. Because the generation of these regulatory T cells is also...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675031/ https://www.ncbi.nlm.nih.gov/pubmed/19325036 http://dx.doi.org/10.1093/intimm/dxp023 |