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Ectodermal-Neural Cortex 1 Down-Regulates Nrf2 at the Translational Level

The transcription factor Nrf2 is the master regulator of a cellular defense mechanism against environmental insults. The Nrf2-mediated antioxidant response is accomplished by the transcription of a battery of genes that encode phase II detoxifying enzymes, xenobiotic transporters, and antioxidants....

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Jun, Zhang, Donna D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675063/
https://www.ncbi.nlm.nih.gov/pubmed/19424503
http://dx.doi.org/10.1371/journal.pone.0005492