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Ectodermal-Neural Cortex 1 Down-Regulates Nrf2 at the Translational Level
The transcription factor Nrf2 is the master regulator of a cellular defense mechanism against environmental insults. The Nrf2-mediated antioxidant response is accomplished by the transcription of a battery of genes that encode phase II detoxifying enzymes, xenobiotic transporters, and antioxidants....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675063/ https://www.ncbi.nlm.nih.gov/pubmed/19424503 http://dx.doi.org/10.1371/journal.pone.0005492 |