De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype

Prions are the proteinaceous infectious agents responsible for Transmissible Spongiform Encephalopathies. Compelling evidence supports the hypothesis that prions are composed exclusively of a misfolded version of the prion protein (PrP(Sc)) that replicates in the body in the absence of nucleic acids...

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Detalles Bibliográficos
Autores principales: Barria, Marcelo A., Mukherjee, Abhisek, Gonzalez-Romero, Dennisse, Morales, Rodrigo, Soto, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675078/
https://www.ncbi.nlm.nih.gov/pubmed/19436715
http://dx.doi.org/10.1371/journal.ppat.1000421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675078/
https://www.ncbi.nlm.nih.gov/pubmed/19436715
http://dx.doi.org/10.1371/journal.ppat.1000421

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