Cargando…
De Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype
Prions are the proteinaceous infectious agents responsible for Transmissible Spongiform Encephalopathies. Compelling evidence supports the hypothesis that prions are composed exclusively of a misfolded version of the prion protein (PrP(Sc)) that replicates in the body in the absence of nucleic acids...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675078/ https://www.ncbi.nlm.nih.gov/pubmed/19436715 http://dx.doi.org/10.1371/journal.ppat.1000421 |