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Transient in utero disruption of Cystic Fibrosis Transmembrane Conductance Regulator causes phenotypic changes in Alveolar Type II cells in adult rats

BACKGROUND: Mechanicosensory mechanisms regulate cell differentiation during lung organogenesis. We have previously demonstrated that cystic fibrosis transmembrane conductance regulator (CFTR) was integral to stretch-induced growth and development and that transient expression of antisense-CFTR (ASC...

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Detalles Bibliográficos
Autores principales: Gad, Ashraf, Callender, Delon L, Killeen, Erin, Hudak, Joseph, Dlugosz, Malgosia A, Larson, Janet E, Cohen, J Craig, Chander, Avinash
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675516/
https://www.ncbi.nlm.nih.gov/pubmed/19335897
http://dx.doi.org/10.1186/1471-2121-10-24