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Telomere recombination requires the MUS81 endonuclease

Telomerase-negative cancer cells maintain their telomeres via the Alternative Lengthening of Telomeres (ALT) pathway1–3. Although a growing body of evidence demonstrates that the ALT mechanism is a post-replicative telomere recombination process, molecular details of this pathway are largely unknown...

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Detalles Bibliográficos
Autores principales: Zeng, Sicong, Xiang, Tao, Pandita, Tej K., Gonzalez-Suarez, Ignacio, Gonzalo, Susana, Harris, Curtis C., Yang, Qin
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675667/
https://www.ncbi.nlm.nih.gov/pubmed/19363487
http://dx.doi.org/10.1038/ncb1867