Direct Observation of ATP-Induced Conformational Changes in Single P2X(4) Receptors

The ATP-gated P2X(4) receptor is a cation channel, which is important in various pathophysiological events. The architecture of the P2X(4) receptor in the activated state and how to change its structure in response to ATP binding are not fully understood. Here, we analyze the architecture and ATP-in...

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Detalles Bibliográficos
Autores principales: Shinozaki, Youichi, Sumitomo, Koji, Tsuda, Makoto, Koizumi, Schuichi, Inoue, Kazuhide, Torimitsu, Keiichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675908/
https://www.ncbi.nlm.nih.gov/pubmed/19419241
http://dx.doi.org/10.1371/journal.pbio.1000103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675908/
https://www.ncbi.nlm.nih.gov/pubmed/19419241
http://dx.doi.org/10.1371/journal.pbio.1000103

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