Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction

AIMS: The mechanisms involved in hypoxic pulmonary vasoconstriction (HPV) are not yet fully defined. The aim of the study was to determine the role of protein kinase C ζ (PKCζ) and neutral sphingomyelinase (nSMase) in HPV. METHODS AND RESULTS: Ceramide content was measured by immunocytochemistry and...

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Detalles Bibliográficos
Autores principales: Cogolludo, Angel, Moreno, Laura, Frazziano, Giovanna, Moral-Sanz, Javier, Menendez, Carmen, Castañeda, Javier, González, Constancio, Villamor, Eduardo, Perez-Vizcaino, Francisco
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675929/
https://www.ncbi.nlm.nih.gov/pubmed/19088082
http://dx.doi.org/10.1093/cvr/cvn349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675929/
https://www.ncbi.nlm.nih.gov/pubmed/19088082
http://dx.doi.org/10.1093/cvr/cvn349

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