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Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction
AIMS: The mechanisms involved in hypoxic pulmonary vasoconstriction (HPV) are not yet fully defined. The aim of the study was to determine the role of protein kinase C ζ (PKCζ) and neutral sphingomyelinase (nSMase) in HPV. METHODS AND RESULTS: Ceramide content was measured by immunocytochemistry and...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675929/ https://www.ncbi.nlm.nih.gov/pubmed/19088082 http://dx.doi.org/10.1093/cvr/cvn349 |