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Genetic Variation in ANGPTL4 Provides Insights into Protein Processing and Function

Angiopoietin-like protein 4 (ANGPTL4) is a secreted protein that modulates the disposition of circulating triglycerides (TG) by inhibiting lipoprotein lipase (LPL). Here we examine the steps involved in the synthesis and post-translational processing of ANGPTL4, and the effects of a naturally occurr...

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Detalles Bibliográficos
Autores principales: Yin, Wu, Romeo, Stefano, Chang, Shurong, Grishin, Nick V., Hobbs, Helen H., Cohen, Jonathan C.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676053/
https://www.ncbi.nlm.nih.gov/pubmed/19270337
http://dx.doi.org/10.1074/jbc.M900553200