FGF9 monomer/dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

The spontaneous dominant mouse mutant, Elbow-knee-synostosis (Eks), exhibits elbow and knee joint synosotsis, and premature fusion of cranial sutures. Here we identify a missense mutation in the Fgf9 gene that is responsible for the Eks mutation. Through investigation of the pathogenic mechanisms of...

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Detalles Bibliográficos
Autores principales: Harada, Masayo, Murakami, Hirotaka, Okawa, Akihiko, Okimoto, Noriaki, Hiraoka, Shuichi, Nakahara, Taka, Akasaka, Ryogo, Shiraishi, Yo-ichi, Futatsugi, Noriyuki, Mizutani-Koseki, Yoko, Kuroiwa, Atsushi, Shirouzu, Mikako, Yokoyama, Shigeyuki, Taiji, Makoto, Iseki, Sachiko, Ornitz, David M., Koseki, Haruhiko
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676118/
https://www.ncbi.nlm.nih.gov/pubmed/19219044
http://dx.doi.org/10.1038/ng.316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676118/
https://www.ncbi.nlm.nih.gov/pubmed/19219044
http://dx.doi.org/10.1038/ng.316

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