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Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people

BACKGROUND: Simvastatin reduces cardiovascular mortality and morbidity but, as with other HMG-CoA reductase inhibitors, can cause significant muscle toxicity and has been associated with elevations of liver transaminases. METHODS: Muscle and liver adverse effects of simvastatin 40 mg daily were eval...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676245/
https://www.ncbi.nlm.nih.gov/pubmed/19442259
http://dx.doi.org/10.1186/1472-6904-9-6