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Folding machineries displayed on a cation-exchanger for the concerted refolding of cysteine- or proline-rich proteins

BACKGROUND: Escherichia coli has been most widely used for the production of valuable recombinant proteins. However, over-production of heterologous proteins in E. coli frequently leads to their misfolding and aggregation yielding inclusion bodies. Previous attempts to refold the inclusion bodies in...

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Detalles Bibliográficos
Autores principales: Lee, Dae-Hee, Kim, Sung-Gun, Kweon, Dae-Hyuk, Seo, Jin-Ho
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676282/
https://www.ncbi.nlm.nih.gov/pubmed/19323835
http://dx.doi.org/10.1186/1472-6750-9-27