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Folding machineries displayed on a cation-exchanger for the concerted refolding of cysteine- or proline-rich proteins
BACKGROUND: Escherichia coli has been most widely used for the production of valuable recombinant proteins. However, over-production of heterologous proteins in E. coli frequently leads to their misfolding and aggregation yielding inclusion bodies. Previous attempts to refold the inclusion bodies in...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676282/ https://www.ncbi.nlm.nih.gov/pubmed/19323835 http://dx.doi.org/10.1186/1472-6750-9-27 |