A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repair

BACKGROUND: Current strategies for gene therapy of inherited diseases consist in adding functional copies of the gene that is defective. An attractive alternative to these approaches would be to correct the endogenous mutated gene in the affected individual. This study presents a quantitative compar...

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Detalles Bibliográficos
Autores principales: Leclerc, Xavier, Danos, Olivier, Scherman, Daniel, Kichler, Antoine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676283/
https://www.ncbi.nlm.nih.gov/pubmed/19379497
http://dx.doi.org/10.1186/1472-6750-9-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676283/
https://www.ncbi.nlm.nih.gov/pubmed/19379497
http://dx.doi.org/10.1186/1472-6750-9-35

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