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Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice

BACKGROUND: The study tested the hypothesis that apoptosis can prevent and control growth of neoplastic cells. Previous studies in-vitro have shown that the pro-apoptotic P2X(7 )receptor regulates growth of epithelial cells. The specific objective of the present study was to understand to what degre...

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Detalles Bibliográficos
Autores principales: Fu, Wen, McCormick, Tom, Qi, Xiaoping, Luo, Liping, Zhou, Lingyin, Li, Xin, Wang, Bing-Cheng, Gibbons, Heidi E, Abdul-Karim, Fadi W, Gorodeski, George I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676299/
https://www.ncbi.nlm.nih.gov/pubmed/19379509
http://dx.doi.org/10.1186/1471-2407-9-114