Cargando…
Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice
BACKGROUND: The study tested the hypothesis that apoptosis can prevent and control growth of neoplastic cells. Previous studies in-vitro have shown that the pro-apoptotic P2X(7 )receptor regulates growth of epithelial cells. The specific objective of the present study was to understand to what degre...
Autores principales: | Fu, Wen, McCormick, Tom, Qi, Xiaoping, Luo, Liping, Zhou, Lingyin, Li, Xin, Wang, Bing-Cheng, Gibbons, Heidi E, Abdul-Karim, Fadi W, Gorodeski, George I |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676299/ https://www.ncbi.nlm.nih.gov/pubmed/19379509 http://dx.doi.org/10.1186/1471-2407-9-114 |
Ejemplares similares
-
Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis
por: Goldstein, Jill, et al.
Publicado: (2015) -
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis
por: Kong, Ying-Hui, et al.
Publicado: (2018) -
T-cell-expressed proprotein convertase FURIN inhibits DMBA/TPA-induced skin cancer development
por: Vähätupa, Maria, et al.
Publicado: (2016) -
IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis
por: Rothe, Michael, et al.
Publicado: (2013) -
Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment
por: Kang, Mi Ju, et al.
Publicado: (2020)