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Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy
BACKGROUND: Spinal muscular atrophy (SMA) is a neurodegenerative disorder associated with mutations of the survival motor neuron gene SMN and is characterized by muscle weakness and atrophy caused by degeneration of spinal motor neurons. SMN has a role in neurons but its deficiency may have a direct...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676312/ https://www.ncbi.nlm.nih.gov/pubmed/19351384 http://dx.doi.org/10.1186/1741-7015-7-14 |