Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy

BACKGROUND: Spinal muscular atrophy (SMA) is a neurodegenerative disorder associated with mutations of the survival motor neuron gene SMN and is characterized by muscle weakness and atrophy caused by degeneration of spinal motor neurons. SMN has a role in neurons but its deficiency may have a direct...

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Detalles Bibliográficos
Autores principales: Millino, Caterina, Fanin, Marina, Vettori, Andrea, Laveder, Paolo, Mostacciuolo, Maria Luisa, Angelini, Corrado, Lanfranchi, Gerolamo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676312/
https://www.ncbi.nlm.nih.gov/pubmed/19351384
http://dx.doi.org/10.1186/1741-7015-7-14

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