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BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers

BCL6 is a transcriptional repressor that has important functions in lymphocyte differentiation and lymphomagenesis, but there have been no reports of BCL6 expression in gastric cancers. In the present study, we investigated the BCL6 function in gastric cancers. Treatment with TPA resulted in BCL6 de...

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Detalles Bibliográficos
Autores principales: Hirata, Y, Ogasawara, N, Sasaki, M, Mizushima, T, Shimura, T, Mizoshita, T, Mori, Y, Kubota, E, Wada, T, Tanida, S, Kataoka, H, Kamiya, T, Higashiyama, S, Joh, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676553/
https://www.ncbi.nlm.nih.gov/pubmed/19337254
http://dx.doi.org/10.1038/sj.bjc.6605010