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Pi-Pi complexation of bupivacaine and analogues with aromatic receptors: Implications for overdose remediation

The interaction of the important but often overdosed local anesthetic bupivacaine, its structural analogs 2,6-dimethylaniline, and N-methyl-2,6-dimethylacetanilide, and cocaine, with several electron deficient aromatic moieties were studied primarily by proton NMR and UV-visible spectroscopy. In sol...

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Detalles Bibliográficos
Autores principales: Powell, Evon, Lee, Y-H, Partch, Richard, Dennis, Donn, Morey, Timothy, Varshney, Manoj
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676660/
https://www.ncbi.nlm.nih.gov/pubmed/18019843