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Exosome nanovesicles displaying G protein-coupled receptors for drug discovery

Exosomes are naturally occurring nanovesicles that can be tailored to display a broad range of drug targets, including G protein-coupled receptors. Such vesicles provide a new source of complex membrane proteins that are maintained in their native conformation. Given the difficulties to isolate rece...

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Detalles Bibliográficos
Autores principales: Estelles, Angeles, Sperinde, Jeff, Roulon, Thibaut, Aguilar, Barbara, Bonner, Caroline, LePecq, Jean-Bernard, Delcayre, Alain
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676799/
https://www.ncbi.nlm.nih.gov/pubmed/18203441