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Nanoscale amphiphilic macromolecules as lipoprotein inhibitors: the role of charge and architecture

A series of novel amphiphilic macromolecules composed of alkyl chains as the hydrophobic block and poly(ethylene glycol) as the hydrophilic block were designed to inhibit highly oxidized low density lipoprotein (hoxLDL) uptake by synthesizing macromolecules with negatively charged moieties (ie, carb...

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Detalles Bibliográficos
Autores principales: Wang, Jinzhong, Plourde, Nicole M, Iverson, Nicole, Moghe, Prabhas V, Uhrich, Kathryn E
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676825/
https://www.ncbi.nlm.nih.gov/pubmed/18203436