PEGylation of nanoparticles improves their cytoplasmic transport

The efficacy of nucleus-targeted drug- or gene-carrying nanoparticles may be limited by slow transport through the molecularly crowded cytoplasm following endosome escape. Cytoskeletal elements and cellular organelles may pose steric and/or adhesive obstacles to the efficient intracellular transport...

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Detalles Bibliográficos
Autores principales: Suh, Junghae, Choy, Kok-Leong, Lai, Samuel K, Suk, Jung Soo, Tang, Benjamin C, Prabhu, Sudhir, Hanes, Justin
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676827/
https://www.ncbi.nlm.nih.gov/pubmed/18203439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676827/
https://www.ncbi.nlm.nih.gov/pubmed/18203439

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