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Functional Analysis of a Dominant Negative Mutation of Interferon Regulatory Factor 5
BACKGROUND: Interferon regulatory factor (IRF) family members have been implicated as critical transcription factors that function in immune response, hematopoietic differentiation and cell growth regulation. Activation of IRF-5 results in the production of pro-inflammatory cytokines such as TNFα, I...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677155/ https://www.ncbi.nlm.nih.gov/pubmed/19430534 http://dx.doi.org/10.1371/journal.pone.0005500 |