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Transient Nature of Long-Term Nonprogression and Broad Virus-Specific Proliferative T-Cell Responses with Sustained Thymic Output in HIV-1 Controllers

BACKGROUND: HIV-1(+) individuals who, without therapy, conserve cellular anti-HIV-1 responses, present with high, stable CD4(+) T-cell numbers, and control viral replication, facilitate analysis of atypical viro-immunopathology. In the absence of universal definition, immune function in such HIV con...

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Detalles Bibliográficos
Autores principales: Westrop, Samantha J., Qazi, Nadeem A., Pido-Lopez, Jeffrey, Nelson, Mark R., Gazzard, Brian, Gotch, Frances M., Imami, Nesrina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677159/
https://www.ncbi.nlm.nih.gov/pubmed/19434236
http://dx.doi.org/10.1371/journal.pone.0005474