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Neutrophil enhancement of Pseudomonas aeruginosa biofilm development: human F-actin and DNA as targets for therapy

In the cystic fibrosis (CF) airway, chronic infection by Pseudomonas aeruginosa results from biofilm formation in a neutrophil-rich environment. We tested the capacity of human neutrophils to modify early biofilm formation of P. aeruginosa strain PAO1, and an isogenic CF strain isolated early and ye...

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Detalles Bibliográficos
Autores principales: Parks, Quinn M., Young, Robert L., Poch, Katie R., Malcolm, Kenneth C., Vasil, Michael L., Nick, Jerry A.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677169/
https://www.ncbi.nlm.nih.gov/pubmed/19273646
http://dx.doi.org/10.1099/jmm.0.005728-0