Two distinct signalling cascades target the NF-κB regulatory factor c-IAP1 for degradation

c-IAP1 (cellular inhibitor of apoptosis 1) has recently emerged as a negative regulator of the non-canonical NF-κB (nuclear factor κB) signalling cascade. Whereas synthetic IAP inhibitors have been shown to trigger the autoubiquitination and degradation of c-IAP1, less is known about the physiologic...

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Detalles Bibliográficos
Autores principales: Csomos, Rebecca A., Wright, Casey W., Galbán, Stefanie, Oetjen, Karolyn A., Duckett, Colin S.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677214/
https://www.ncbi.nlm.nih.gov/pubmed/19243308
http://dx.doi.org/10.1042/BJ20082140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677214/
https://www.ncbi.nlm.nih.gov/pubmed/19243308
http://dx.doi.org/10.1042/BJ20082140

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