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Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress

BACKGROUND: Oxidative stress (OS) is an important factor in brain aging and neurodegenerative diseases. Certain neurons in different brain regions exhibit selective vulnerability to OS. Currently little is known about the underlying mechanisms of this selective neuronal vulnerability. The purpose of...

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Detalles Bibliográficos
Autores principales: Wang, Xinkun, Zaidi, Asma, Pal, Ranu, Garrett, Alexander S, Braceras, Rogelio, Chen, Xue-wen, Michaelis, Mary L, Michaelis, Elias K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677396/
https://www.ncbi.nlm.nih.gov/pubmed/19228403
http://dx.doi.org/10.1186/1471-2202-10-12