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Defective Peripheral Nerve Development Is Linked to Abnormal Architecture and Metabolic Activity of Adipose Tissue in Nscl-2 Mutant Mice

BACKGROUND: In mammals the interplay between the peripheral nervous system (PNS) and adipose tissue is widely unexplored. We have employed mice, which develop an adult onset of obesity due to the lack the neuronal specific transcription factor Nscl-2 to investigate the interplay between the nervous...

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Detalles Bibliográficos
Autores principales: Ruschke, Karen, Ebelt, Henning, Klöting, Nora, Boettger, Thomas, Raum, Kay, Blüher, Matthias, Braun, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677458/
https://www.ncbi.nlm.nih.gov/pubmed/19436734
http://dx.doi.org/10.1371/journal.pone.0005516