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Attaching and Effacing Escherichia coli Downregulate DNA Mismatch Repair Protein In Vitro and Are Associated with Colorectal Adenocarcinomas in Humans

BACKGROUND: Mucosa-associated Escherichia coli are frequently found in the colonic mucosa of patients with colorectal adenocarcinoma, but rarely in healthy controls. Chronic mucosal E. coli infection has therefore been linked to colonic tumourigenesis. E. coli strains carrying eae (encoding the bact...

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Detalles Bibliográficos
Autores principales: Maddocks, Oliver D. K., Short, Abigail J., Donnenberg, Michael S., Bader, Scott, Harrison, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677459/
https://www.ncbi.nlm.nih.gov/pubmed/19436735
http://dx.doi.org/10.1371/journal.pone.0005517