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How β-Lactam Antibiotics Enter Bacteria: A Dialogue with the Porins
BACKGROUND: Multi-drug resistant (MDR) infections have become a major concern in hospitals worldwide. This study investigates membrane translocation, which is the first step required for drug action on internal bacterial targets. β-lactams, a major antibiotic class, use porins to pass through the ou...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677626/ https://www.ncbi.nlm.nih.gov/pubmed/19434239 http://dx.doi.org/10.1371/journal.pone.0005453 |