Pivotal Role of the α(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis

BACKGROUND: Norepinephrine (NE) modulates the responsiveness of macrophages to proinflammatory stimuli through the activation of adrenergic receptors (ARs). Being part of the stress response, early increases of NE in sepsis sustain adverse systemic inflammatory responses. The intestine is an importa...

Descripción completa

Detalles Bibliográficos
Autores principales: Miksa, Michael, Das, Padmalaya, Zhou, Mian, Wu, Rongqian, Dong, Weifeng, Ji, Youxin, Goyert, Sanna M., Ravikumar, Thanjavur S., Wang, Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677660/
https://www.ncbi.nlm.nih.gov/pubmed/19430535
http://dx.doi.org/10.1371/journal.pone.0005504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677660/
https://www.ncbi.nlm.nih.gov/pubmed/19430535
http://dx.doi.org/10.1371/journal.pone.0005504

Ejemplares similares