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Pivotal Role of the α(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis
BACKGROUND: Norepinephrine (NE) modulates the responsiveness of macrophages to proinflammatory stimuli through the activation of adrenergic receptors (ARs). Being part of the stress response, early increases of NE in sepsis sustain adverse systemic inflammatory responses. The intestine is an importa...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677660/ https://www.ncbi.nlm.nih.gov/pubmed/19430535 http://dx.doi.org/10.1371/journal.pone.0005504 |