SUMOylation of DRIL1 Directs Its Transcriptional Activity Towards Leukocyte Lineage-Specific Genes

DRIL1 is an ARID family transcription factor that can immortalize primary mouse fibroblasts, bypass RAS(V12)-induced cellular senescence and collaborate with RAS(V12) or MYC in mediating oncogenic transformation. It also activates immunoglobulin heavy chain transcription and engages in heterodimer f...

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Detalles Bibliográficos
Autores principales: Prieur, Alexandre, Nacerddine, Karim, van Lohuizen, Maarten, Peeper, Daniel S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677661/
https://www.ncbi.nlm.nih.gov/pubmed/19436740
http://dx.doi.org/10.1371/journal.pone.0005542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677661/
https://www.ncbi.nlm.nih.gov/pubmed/19436740
http://dx.doi.org/10.1371/journal.pone.0005542

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