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Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense, and is a major cause of systemic and neurological disability throughout sub-Saharan Africa. Following early-stage disease, the trypanosomes cross...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677800/ https://www.ncbi.nlm.nih.gov/pubmed/19339256 http://dx.doi.org/10.1093/brain/awp074 |