Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis

Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense, and is a major cause of systemic and neurological disability throughout sub-Saharan Africa. Following early-stage disease, the trypanosomes cross...

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Detalles Bibliográficos
Autores principales: Rodgers, Jean, Stone, Trevor W., Barrett, Michael P., Bradley, Barbara, Kennedy, Peter G. E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677800/
https://www.ncbi.nlm.nih.gov/pubmed/19339256
http://dx.doi.org/10.1093/brain/awp074

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