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Mutations to the histone H3 αN region selectively alter the outcome of ATP-dependent nucleosome-remodelling reactions

Mutational analysis of the histone H3 N-terminal region has shown it to play an important role both in chromatin function in vivo and nucleosome dynamics in vitro. Here we use a library of mutations in the H3 N-terminal region to investigate the contribution of this region to the action of the ATP-d...

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Detalles Bibliográficos
Autores principales: Somers, Joanna, Owen-Hughes, Tom
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677872/
https://www.ncbi.nlm.nih.gov/pubmed/19264807
http://dx.doi.org/10.1093/nar/gkp114